Since the discovery since penicillin, antibiotics have been a powerful weapon for human treatment of pathogenic microorganisms infections, but with the long-term antibiotics widely used, pathogen resistance formation are becoming increasingly serious and urgent requirement to develop new antibiotics, but before looking for new microorganisms the biological difficulty has been getting bigger and bigger. Animal-derived antimicrobial peptide (also known as the discovery of the bactericidal peptide, animal polypeptide antibiotics) for the development of new antibiotics to provide a new broad sources. In recent years, the rapid development of theoretical and applied research on antimicrobial peptides.